NCT06065163

Ultrasound Guided Diuretic Therapy in Type 1 Cardiorenal Syndrome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Instituto Nacional de Cardiologia Ignacio Chavez · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A double-blind, randomized, controlled trial was conducted with the main objective of evaluating if patients with clinical assessment and VExUS reach decongestion faster within a maximum period of 7 days during the hospital stay. Likewise, the study will describe those patients who experience a decrease in serum creatinine (CrS), NT-proBNP at discharge, greater diuretic adjustment, rate of intrahospital readmission, and 30-day mortality.

Conditions

• Cardiorenal Syndrome Type 1

Interventions

Type	Name	Description
OTHER	Diuretic de/escalation based on ultrasound findings (VExUS Score)	Patients allocated in the experimental arm will have diuretic dosing adjusted based on ultrasound findings (VExUS Score)
OTHER	Diuretic de/escalation based on clinical findings (CCS Score)	Patients allocated in the experimental arm will have diuretic dosing adjusted based on clinical findings (CCS Score)

Timeline

• Start date: 2022-09-01
• Primary completion: 2024-12-31
• Completion: 2025-03-31
• First posted: 2023-10-03
• Last updated: 2023-10-05

Locations

1 site across 1 country: Mexico