NCT06064838

Effects of Cacao Flavonoids in Long COVID-19 Patients (FLALOC)

Effects of Cacao Flavonoids in Long COVID-19 Patients with Chronic Fatigue (FLALOC)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: Guillermo Ceballos Reyes · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo to evaluate the effect of daily consumption of a cacao supplement on inflammation, endothelial damage, handgrip strength, fatigue scale and quality of life.

Detailed description

The study use a triple blind, placebo-controlled design enrolling male and female subjects between 30-70 yo distributed homogeneously at random in two groups: the control group (Placebo) and the intervention group (Cacao Flavonoids) both groups affected for 90 days. The variables to consider will be: Interleukins (IL-1b, IL-6), Tumoral Necrosis Factor alpha (TNF-α) and syndecan-1. For physical performance is evaluated the handgrip strength. The investigators also assessed quality of life using the Health Related QoL (EQ-5D) questionnaire, and the numerical fatigue rating scale.

Conditions

• Long Covid19
• Fatigue Syndrome, Chronic

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Flavonoids	1 capsule every 12h for 90 days

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-08-01
• Completion: 2024-09-30
• First posted: 2023-10-03
• Last updated: 2024-10-01

Locations

1 site across 1 country: Mexico