NCT06061185

Multimodal Computed Tomography in Patients With Acute Hemorrhagic Stroke

Multimodal Computed Tomography in Patients With Acute Hemorrhagic Stroke (MCTAHS)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 10,000 (estimated)
• Sponsor: Xiaolin Chen, MD · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

Acute hemorrhagic stroke is a series of neurosurgical diseases characterized by bleeding with high morbidity and mortality. It accounts for about 20% of all strokes worldwide and mainly includes subtypes such as intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH). Multimodal computed tomography including non-contrast computed tomography, computed tomography angiography and computed tomography perfusion, is of great important in understanding pathophysiological changes, evaluating prognosis and guiding interventions in these diseases.

Detailed description

Study overview: The data of the population in the MACTAHS study will be prospectively collected. The CT strategies for acute hemorrhagic stroke are mainly three categories: non-contrast computed tomography, computed tomography angiography and computed tomography perfusion. Each participants will be followed at least until 1 year after discharge. Finally, investigators will clarify the prognostic value of multimodal CT for patients with acute hemorrhagic stroke. Sample size: About 10000 patients will be enrolled in this study. All the population will be expected to undergo non-contrast computed tomography, computed tomography angiography and computed tomography perfusion. Study endpoints: Neurological functional outcomes, delayed ischemia and infarction, recurrent bleeding, cognition and emotional dysfunction, systemic in-hospital systemic complications, rehabilitation and recovery status will be evaluated and follow-up would be completed.

Conditions

• Acute Hemorrhagic Stroke

Interventions

Type	Name	Description
DEVICE	Multimodal CT	Non-contrast computed tomography, computed tomography angiography and computed tomography perfusion

Timeline

• Start date: 2020-01-01
• Primary completion: 2032-03-01
• Completion: 2032-04-01
• First posted: 2023-09-29
• Last updated: 2025-04-04

Locations

1 site across 1 country: China