NCT06060548

Role of Novel ILR in the Management of PVCs

Role of a Novel Implantable Loop Recorder in the Management of Premature Ventricular Contractions

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Kansas City Heart Rhythm Research Foundation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This prospective, observational study is a single center clinical registry of patients referred for management of symptomatic or asymptomatic Premature Ventricular Contractions (PVCs). Subjects will be followed through 12 months. The study will enroll approximately 50 patients.

Detailed description

This study is intended to monitor patients presenting with Premature Ventricular Contractions (PVCs) and ventricular arrhythmias using implantable loop recorders (ILRs) from the time of their initial presentation of PVCs to assess for the incidence of all cardiac arrhythmias detected with long term monitoring in this population. It is also intended to evaluate for clinical, biomarker and radiological evidence of myocarditis in this cohort to understand association with incident arrhythmias and understand the role of implantable loop recorders (ILRs)in managing these patients.

Conditions

• PVC - Premature Ventricular Contraction
• Myocarditis

Interventions

Type	Name	Description
OTHER	Monitoring of patients presenting with PVCs	Patients presenting with PVCs and ventricular arrhythmias will be monitored using ILRs from the time of their initial presentation of PVCs to assess for the incidence of all cardiac arrhythmias. They will also be evaluated for clinical, biomarker and radiological evidence of myocarditis to understand association with incident arrhythmias.

Timeline

• Start date: 2022-04-20
• Primary completion: 2025-09-01
• Completion: 2025-12-01
• First posted: 2023-09-29
• Last updated: 2025-08-28

Locations

6 sites across 1 country: United States

Regulatory

• FDA-regulated device study