Trials / Recruiting
RecruitingNCT06058182
RNA as Prognostic Biomarkers in Patients With Acute Coronary Syndrome
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 70 (estimated)
- Sponsor
- IRCCS Policlinico S. Donato · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Identify circulating protein-coding (mRNAs) or non-coding (ncRNAs) transcripts (ACS\_signature) predictive of ventricular dysfunction in ACS patients undergoing PCI.
Detailed description
Perform an observational, prospective study involving the evaluation of circulating biomarkers predictive of ventricular dysfunction (FE \<45%) in patients with ACS. In particular, will be to verify whether there are circulating transcripts in peripheral blood, coding or not for proteins (mRNAs or ncRNAs), modulated differently in patients with ACS (ACS\_signature) undergoing PCI, distinguished on the basis of evolution towards ventricular dysfunction. The study will be based on whole genome transcriptomic analysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | blood draws | Pre-procedure, post-procedure (12-24 h), 6-month, and 12-month blood draws |
Timeline
- Start date
- 2020-07-13
- Primary completion
- 2026-01-30
- Completion
- 2027-01-30
- First posted
- 2023-09-28
- Last updated
- 2023-10-06
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT06058182. Inclusion in this directory is not an endorsement.