Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06057948

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

Phase II Trial of a Bivalent Vaccine With the Immunological Adjuvant OPT-821 (QS-21), in Combination With Randomization of Oral β-glucan, for High-Risk Neuroblastoma

Status
Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
94 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The purpose of this study is to test which treatment schedule of β-glucan with bivalent vaccine is more effective for participants with high-risk neuroblastoma that is in complete remission.

Conditions

Interventions

TypeNameDescription
BIOLOGICALOPT-821 (QS-21)Comprised of the immunological adjuvant OPT-821 (QS-21)
DIETARY_SUPPLEMENToral β-glucanParticipants will be randomized to receive this agent in two different schedules

Timeline

Start date
2023-09-21
Primary completion
2027-03-21
Completion
2027-03-21
First posted
2023-09-28
Last updated
2026-04-02

Locations

7 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT06057948. Inclusion in this directory is not an endorsement.