NCT06057350

Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR

Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR (SCAR)- a Randomized Controlled Trial

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 304 (estimated)
• Sponsor: Norwegian Department of Health and Social Affairs · Other Government
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Randomized head-to-head comparison trial among patients who have undergone incomplete endoscopic resection of early colon cancer to evaluate the benefits, harms and burdens, as well as the ecological footprint and cost-effectiveness of endoscopic full thickness resection (eFTR), a minimally invasive endoscopic treatment with a colonoscope, as compared to standard-of-care surgery. Co-primary endpoints are * Rate of severe adverse events classified as grade III to V according to the Clavien Dindo classification within 30-days after study treatment * CRC recurrence or sign of lymph nodes or distant metastases at 3 years after randomization comparing the two treatment groups (eFTR versus surgery).

Conditions

• Treatment Side Effects
• Colorectal Cancer

Interventions

Type	Name	Description
PROCEDURE	Tumor removal	Removal of incompletely removed early-stage colon cancer

Timeline

• Start date: 2023-10-27
• Primary completion: 2031-09-01
• Completion: 2033-09-01
• First posted: 2023-09-28
• Last updated: 2024-02-16

Locations

3 sites across 2 countries: Norway, Poland