NCT06054750

Testing Regional anesthesia Techniques For Up And Early Discharge Following Knee arthroplasty - a Feasibility Study

Testing Regional anesthesia Techniques For Up And Early Discharge Following Knee arthroplasty: Quality Of Recovery Through Patient Reporting - a Feasibility Study

• Status: Not Yet Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 226 (estimated)
• Sponsor: McMaster University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without adductor canal catheter infusion.

Detailed description

Knee osteoarthritis (KOA) is a leading cause of chronic knee pain and disability, with a lifetime prevalence of 45%. Treatment for symptomatic KOA includes physical therapy, oral anti-inflammatory medications and intra-articular steroid injections, with total knee arthroplasty (TKA) (or knee replacement) as the definitive treatment. Acute postoperative pain is common after TKA, leading to increased opioid consumption and increased hospital length of stay. Pain control following TKA has been investigated with interventions such as intrathecal morphine, nerve blocks, and periarticular joint injection (PAI). PAI and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing TKA. The aim of this study is to assess postoperative patient-reported quality of recovery after TKA with PAI and single shot adductor canal block with or without adductor canal catheter infusion.

Conditions

• Arthroplasty, Replacement, Knee

Interventions

Type	Name	Description
DRUG	Ropivacaine	800 mg ropivacaine in continuous infusion adductor canal block (400 mL total volume)
DRUG	Normal saline	400 mL normal saline in continuous infusion adductor canal block (400 mL total volume)

Timeline

• Start date: 2025-01-01
• Primary completion: 2027-03-31
• Completion: 2027-06-30
• First posted: 2023-09-26
• Last updated: 2024-10-22

Locations

1 site across 1 country: Canada