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Active Not RecruitingNCT06052800

Agalsidase Beta Long-Term Treatment Outcome for Fabry Disease Patients With IVS4 Mutation in Taiwan

An Observational Study of Enzyme Replacement Therapy-Naïve and Agalsidase Beta-Treated Fabry Disease Patients With GLA IVS4 919 G>A Mutation in Taiwan

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
78 (actual)
Sponsor
Sanofi · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a national, multicenter, observational, cohort study designed to assess clinical outcomes upon agalsidase beta treatment, to characterize the clinical manifestations, and to collect the natural history on male and female Fabry disease adult patients who carry the GLA IVS4. This study aims to retrospectively and prospectively investigate the disease natural history, clinical manifestations, and the treatment outcomes upon agalsidase beta in Fabry disease (FD) patients carrying the GLA IVS4 mutation from medical records, physician assessments, and patient-reported outcomes.

Detailed description

Study Design Time Perspective: Retrospective and Prospective

Conditions

Timeline

Start date
2023-09-13
Primary completion
2026-09-10
Completion
2026-09-10
First posted
2023-09-25
Last updated
2025-03-21

Locations

5 sites across 1 country: Taiwan

Source: ClinicalTrials.gov record NCT06052800. Inclusion in this directory is not an endorsement.

Agalsidase Beta Long-Term Treatment Outcome for Fabry Disease Patients With IVS4 Mutation in Taiwan (NCT06052800) · Clinical Trials Directory