NCT06051838

Prognostic Value of Tumor Deposits for Patients With Papillary Thyroid Carcinoma

Prognostic Value of Tumor Deposits for Patients With Papillary Thyroid Carcinoma: a Retrospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 541 (actual)
• Sponsor: Nanfang Hospital, Southern Medical University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Tumor deposits (TD), nodules in the peritumoral adipose tissue with no architectural residue of lymph node, which is a definition often being confusing to the extranodal extension (ENE), have been described in several malignancies and linked to a worse prognosis. In gastric cancer and colon cancer, TD and ENE should be distinguished and collected separately in 8th AJCC manual. However, in thyroid cancer, TD as a collection variable was absence in both the 8th AJCC manual and the 2015 ATA guideline. This is a study that revealed the presence of TD by reviewing a large number of papillary thyroid carcinoma (PTC) specimens and explored its prognostic value by constructing a nomogram to accurately predict disease-free survival in PTC patients.

Conditions

• Exploring the Prognostic Value of Tumor Deposits PTC Patients

Interventions

Type	Name	Description
PROCEDURE	surgery	if the patients is TD positive, we recommond careful surgery and pathological examination.

Timeline

• Start date: 2022-11-01
• Primary completion: 2023-02-28
• Completion: 2023-03-30
• First posted: 2023-09-25
• Last updated: 2023-09-25

Locations

1 site across 1 country: China