NCT06049355

EMBRACE: Exercising Together

EMBark on RAdiation Therapy With a Clinic-based Exercise Program: EXERCISING TOGETHER

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: OHSU Knight Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This phase II trial tests how well an exercise intervention, Exercising Together, works in preventing declines in physical and mental health in couples during radiation treatment for cancer. Treatments for cancer can cause side effects such as fatigue as well as strain on relationships. Exercising Together is a partnered exercise program that adds communication, collaboration and support between partners during exercise to fortify the relationship and amplify the benefits of physical training. Exercising Together program may be effective on the mental and physical health of couples during radiation treatment for cancer.

Detailed description

PRIMARY OBJECTIVE: I. To test the effectiveness and mechanisms of the adapted Exercise Together intervention on mental and physical health of couples (Aims 1 \& 2). SECONDARY OBJECTIVE: I. To gain better understanding of the implementation context and implementation outcomes (Aim 3). OUTLINE: Patients are randomized to 1 of 2 arms. ARM I: Patients and partners undergo Exercising Together exercise program during radiation therapy on study. Patients also undergo collection of blood samples throughout the trial. ARM II: Patients and partners receive educational materials specific to exercise. Patients also undergo collection of blood samples throughout the trial.

Conditions

• Breast Carcinoma
• Prostate Carcinoma

Interventions

Type	Name	Description
OTHER	Exercise Intervention	Undergo Exercise Together exercise program, a supervised group exercise program delivered online, using a live remote format
PROCEDURE	Biospecimen Collection	Undergo collection of blood samples
OTHER	Educational Intervention	Receive educational materials

Timeline

• Start date: 2024-04-18
• Primary completion: 2028-06-30
• Completion: 2028-09-01
• First posted: 2023-09-22
• Last updated: 2025-05-29

Locations

1 site across 1 country: United States