NCT06047795

Endurance Training in Patients With Post-TB Lung Disease

Effect of Endurance Training On Functional Capacity and Quality of Life in Patients With Post-TB Lung Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Riphah International University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

To determine the effects of endurance training on functional capacity and QOL(Quality of life) in patients with post-TB (tuberculosis) lung disease. Post-tuberculosis lung disease is a major health concern nowadays. There is limited evidence in the literature regarding the rehabilitation of patients with cured tuberculosis which leads to post-TB complications.

Detailed description

Adults with post-TB respiratory symptoms experience skeletal muscle weakness due to inactivity, systemic inflammation, and poor nutrition, which is frequently made worse by poverty. Such patients experience a vicious cycle that includes decreased body weight, increasing morbidity, and higher mortality. People with Chronic Respiratory Diseases frequently avoid exercise, which causes them to lose motivation and decondition. This cycle of decline continues. In Pakistan, there is no concept of pulmonary rehabilitation for TB patients. The current study will attempt to fill this literature gap and also promote the concept of pulmonary rehabilitation for post-tuberculosis patients in Pakistan.

Conditions

• Tuberculosis
• Post-Tuberculous Pleural Fibrosis
• Post-Tuberculous Bronchiectasis

Interventions

Type	Name	Description
OTHER	Experimental	Cycling 2 days per week with Borg dyspnea 4-6 level for 15-20 minutes/ day with 5 minutes warm-up and cool-down. Strengthening exercises for upper limb muscles (pull-ups and biceps curls) and for lower limb muscles (sit-to-stand and step-up exercises) with 3 sets of 8-12 repetitions \* 2 days per week. Pursed Lip breathing exercise 3 sets of 5-10 repetitions for 6 weeks
OTHER	Control	Usual care: frontal chest radiographs, verbal advice to quit smoking, and reduce exposure to biomass smoke. Spirometry to screen for airway diseases. Antibiotic and systemic glucocorticoid therapy.

Timeline

• Start date: 2023-09-11
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2023-09-21
• Last updated: 2024-09-04

Locations

1 site across 1 country: Pakistan