NCT06047743

Comparison of Upper and Lower Extremity Isometrics on Cognition in Healthy Adolescents

Comparison of Upper and Lower Extremity Isometrics on Cognition in Healthy Adolescents: A Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (actual)
• Sponsor: Riphah International University · Academic / Other
• Sex: All
• Age: 12 Years – 18 Years
• Healthy volunteers: Accepted

Summary

This study aims to compare the effects of upper and lower-extremity isometrics on cognition in healthy adolescents.

Detailed description

The literature suggests a positive impact of isometrics on cognition. Identifying how cognitive results would differ in upper vs. lower extremity isometric groups is the main objective of the study. for cognitive assessment, different aspects of cognition will be measured by all computer-based tools (except for Trail making A and B).

Conditions

• Healthy Adolescents

Interventions

Type	Name	Description
OTHER	Alternating unilateral Isometric Handgrip Exercise	Participants (n=19) will be performing alternating unilateral Isometric Handgrip exercises using a dynamometer for 3-5 days a week for a total duration of 8 weeks. The participant will be seated with their elbow resting on the armrest and wrists off the supporting surface. A single session will consist of 4 sets of 30%MVC (calculated by dynamometer) of handgrip exercise with a maximum 2 minutes contraction time/ hold time followed by a rest period/ recovery period of 1 minute during each set.
OTHER	Dominant knee extension Isometric Exercise	Participants enrolled in this group will be performing dominant leg isometric knee extension. The knee will be 35° flexed from a fully extended position when performing isometric knee extension using a hand-held dynamometer retrained by a belt. The intervention duration will be 8 weeks. A single session will consist of performing 4 sets of 30% MVC (calculated using a dynamometer) of unilateral knee extension isometrics with a maximum 2 minutes contraction time/ hold time followed by a rest/ recovery period of 1 minute during each set.

Timeline

• Start date: 2023-09-22
• Primary completion: 2023-12-31
• Completion: 2024-01-30
• First posted: 2023-09-21
• Last updated: 2024-05-21

Locations

1 site across 1 country: Pakistan