NCT06044207

Biomarkers and Risk Factors for Perioperative Neurocognitive Dysfunction in Elderly Patients

Biomarkers and Risk Factors for Perioperative Neurocognitive Disorders in Elderly Non-neurosurgical Patients

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Jinan Central Hospital · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Basic information and biological samples of patients were collected preoperatively and intraoperatively, and patients were divided into case and control groups by cognitive function assessment postoperatively, and risk factors and biomarkers of perioperative cognitive dysfunction were derived by analyzing and statistically processing basic information and biological samples.

Conditions

• Perioperative Neurocognitive Dysfunction

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Pittsburgh sleep quality index	The scale is suitable for evaluating sleep quality in patients with sleep disorders and psychiatric disorders, as well as for assessing sleep quality in the general population.
DIAGNOSTIC_TEST	Self-rating depression scale	The scale is easy to use, can fairly intuitively reflect whether the patient has depression and the degree of depression, has been widely used in outpatient gross screening, mood state assessment.
DIAGNOSTIC_TEST	Montreal Cognitive Assessment	The scale is a tool used for rapid screening of mild cognitive dysfunction to identify patients with preoperative cognitive dysfunction

Timeline

• Start date: 2023-06-01
• Primary completion: 2025-06-01
• Completion: 2026-01-01
• First posted: 2023-09-21
• Last updated: 2023-09-21

Locations

1 site across 1 country: China