NCT06043882

Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After COVID- 2019 .

Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After Corona Virus Disease of 2019 Infection.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 55 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this observational study is to learn about sarcoidosis development after COVID-19 infection. The main question it aims to answer is: * prevalence of Sarcoidosis among patients previously infected with COVID-19. Participants will: * provide previous positive RT-PCR for COVID-19 * Have computed tomography of the Chest with suggestive findings of sarcoidosis * Have bronchoscopic guided biopsies and pathological analysis to detect number of patients with sarcoidosis.

Detailed description

This prospective cross sectional study was performed on a total of 55 patients with mediastinal and /or hilar lymphadenopathy with or without lung infiltrates referred to Bronchoscopy unit , Chest department, Ain-Shams University hospital for biopsy taking and diagnosis. All patients were subjected to the following : history taking , clinical examination , radiological assessment by computed tomography (CT )chest , fiberoptic bronchoscopy where biopsies were taken either by conventional-Trans-bronchial needle aspiration (c-TBNA) , endo-bronchial ultrasound (EBUS-TBNA) or direct forceps biopsies and sent for histopathological examination and if the patient had past history of COVID-19 infection with previous positive reverse transcriptase- polymerase chain reaction assay (RT-PCR).

Conditions

• Sarcoidosis
• COVID-19

Interventions

Type	Name	Description
PROCEDURE	flexible bronchoscopy	fiberoptic bronchoscopy was done where biopsies were taken either by conventional TBNA (c-TBNA) , EBUS-TBNA or direct forceps biopsies and sent for histopathological examination

Timeline

• Start date: 2022-11-01
• Primary completion: 2023-04-30
• Completion: 2023-05-30
• First posted: 2023-09-21
• Last updated: 2023-09-22

Locations

1 site across 1 country: Egypt