NCT06043349

Effectiveness and Safety of Platelet-rich Plasma and Topical 5% Minoxidil Combination in Male Androgenetic Alopecia

Effectiveness and Safety of Platelet-rich Plasma and Topical 5% Minoxidil Combination Compared to Topical 5% Minoxidil Monotherapy in Male Androgenetic Alopecia

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to learn about the effectiveness and safety of platelet-rich plasma (PRP) and topical 5% minoxidil combination therapy compared with topical 5% minoxidil monotherapy in male androgenetic alopecia. The main questions it aims to answer are: * Is there a difference in average change of hair density between groups that were given a combination of PRP injection and topical minoxidil compared to topical minoxidil as monotherapy? * Is there a difference in average change of hair thickness between groups that were given a combination of PRP and topical minoxidil compared to topical minoxidil as monotherapy? * Are there any differences in side effects between groups that were given combination of PRP and topical minoxidil compared to topical minoxidil as monotherapy?

Detailed description

The trial will be held for three months in Jakarta, Indonesia. Participants are required to undergo hair examinations every 4 weeks, for a total of 4 visits. Researchers will compare groups that were given a combination of PRP and topical minoxidil compared to topical minoxidil alone as a control group. Hair density, hair thickness, and overall side effects of treatment will be measured at each visit.

Conditions

• Androgenetic Alopecia

Interventions

Type	Name	Description
COMBINATION_PRODUCT	Platelet-Rich Plasma and Topical 5% Minoxidil	The intervention group will receive three PRP injections during three months in addition to the topical 5% minoxidil.
DRUG	Topical 5% Minoxidil	The intervention group will receive topical 5% minoxidil as standard therapy for male androgenetic alopecia.

Timeline

• Start date: 2023-06-01
• Primary completion: 2023-09-01
• Completion: 2023-09-30
• First posted: 2023-09-21
• Last updated: 2023-09-21

Locations

1 site across 1 country: Indonesia