NCT06042933

Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair

Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair: A Comparative Study in Egyptian Tertiary Health Care Center

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate safety and benefits of early oral feeding compared to traditional delayed oral feeding in patients undergoing perforated peptic ulcer repairs. Study population \& Sample size :(

Detailed description

Study Design: This study is a single-center, prospective, parallel arm, randomized controlled trial. Patients will be randomly assigned in 1:1 ratio to receive either delayed oral feeding or early oral feeding. Methods: Patients will be randomly assigned into two groups. Group A patients followed an early oral feeding protocol(12 hours), and Group B received delayed oral feeding (72 hours). Outcome parameter : The outcomes are incidence of postoperative complications including Postoperative repair leakage, Infection-related postoperative complications , Number of days of hospital stay and return of bowel function and Diet intolerance.

Conditions

• Peptic Ulcer Perforation

Interventions

Type	Name	Description
OTHER	Post operative early oral feeding	To start oral feeding 6 hours after perforated peptic ulcer repairs
OTHER	Traditional delayed oral Feeding Post-perforated Peptic Ulcer Repairs	To start oral feeding after 48 hours

Timeline

• Start date: 2023-03-02
• Primary completion: 2024-10-25
• Completion: 2024-11-01
• First posted: 2023-09-21
• Last updated: 2025-08-29

Locations

1 site across 1 country: Egypt