NCT06042387

Genome Analysis Across Populations in Inflammatory Bowel Disease

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 150 (estimated)
• Sponsor: Mount Sinai Hospital, Canada · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Objective: To use clinical, genetic and genome analysis to better understand and define the genetic and environmental factors that contribute to IBD within affected populations.

Detailed description

Background: Inflammatory bowel disease (IBD) is a chronic, and often disabling, disorder of the intestines characterized by dysregulation of mucosal immune response. Recent data suggests that the incidence and prevalence rates among all populations may be increasing due to constantly changing environmental exposures. The goal of the study is to identify susceptible genes that contribute to the pathogenesis of IBD in affected individuals.

Conditions

• Ulcerative Colitis
• Healthy
• Crohn Disease
• Inflammatory Bowel Diseases

Interventions

Type	Name	Description
GENETIC	Blood or saliva sample collection	Blood or saliva sample \& clinical data collection

Timeline

• Start date: 2022-05-01
• Primary completion: 2027-05-01
• Completion: 2027-09-01
• First posted: 2023-09-18
• Last updated: 2025-03-25

Locations

1 site across 1 country: Canada