NCT06042270

Firefighter Thermoregulatory Responses in Active Fire with Betaine Supplementation

Thermoregulatory Responses of Betaine Supplementation in Firefighters During Live Burn

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: Michael J. Ormsbee · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to compare betaine supplementation to placebo in firefighters undergoing live burn training regarding thermoregulation and inflammation. The main questions it aims to answer are: * Does betaine supplementation mitigate rises in core temperature during firefighter live burn training? * Does betaine supplementation decrease inflammation from firefighter training? * Does betaine supplementation increase total body water stores? Participants will supplement with betaine for 1 month and complete: * Total Body Water measures * Body Composition measures * Live Burn training with Core Temperature Measurements * Provide Salivary samples

Conditions

• Body Temperature Changes
• Body Water Dehydration
• Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Betaine	3 grams per day for \~4 weeks
DIETARY_SUPPLEMENT	Placebo	3 grams per day for \~4 weeks

Timeline

• Start date: 2023-12-20
• Primary completion: 2024-03-01
• Completion: 2024-09-01
• First posted: 2023-09-18
• Last updated: 2024-10-17

Locations

1 site across 1 country: United States