Trials / Completed
CompletedNCT06040229
Retrospective Study in FFPE Samples From Younger Patients With Rhabdomyosarcoma
Mechanism of Children With Relapsed and Refractory Rhabdomyosarcoma (RMS)
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 6 (actual)
- Sponsor
- Shandong First Medical University · Academic / Other
- Sex
- All
- Age
- 1 Year – 18 Years
- Healthy volunteers
- Not accepted
Summary
This retrospective study is looking into mechanisms of drug therapy resistance in FFPE samples in recurrent and refractory Rhabdomyosarcoma (RMS) in pediatric patients who have experienced lung recurrence. The study employs advanced techniques such as single-cell transcriptomics and spatial transcriptomics to gain a comprehensive understanding of these mechanisms.
Detailed description
This research seeks to enhance our understanding of drug resistance mechanisms in recurrent and refractory RMS in pediatric patients, particularly in the context of lung recurrence. The utilization of cutting-edge techniques like single-cell transcriptomics and spatial transcriptomics allows for a more in-depth and comprehensive analysis of the molecular and spatial aspects of drug resistance in this challenging pediatric cancer.
Conditions
- Alveolar Childhood Rhabdomyosarcoma
- Embryonal Childhood Rhabdomyosarcoma
- Recurrent Childhood Rhabdomyosarcoma
Timeline
- Start date
- 2023-04-01
- Primary completion
- 2023-07-01
- Completion
- 2023-09-01
- First posted
- 2023-09-15
- Last updated
- 2023-09-15
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT06040229. Inclusion in this directory is not an endorsement.