NCT06040021

Distinct Metastatic Phenotypes Between Early-onset and Late-onset Colorectal Cancer

Integrated Analysis of Multi-center Cohorts and Bulk RNA-sequencing Data Reveal Distinct Metastatic Phenotypes Between Early-onset and Late-onset Colorectal Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 15,244 (actual)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 16 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

The clinical and pathological features of early-onset colorectal cancer (EOCRC) differ from those of late-onset colorectal cancer (LOCRC). Our research aims to thoroughly elucidate the distinctions between them by analyzing clinical prognosis, metastatic patterns, gene expression, and genomic mutation profiles. Our deliberation will uncover latent strategies for personalized therapeutic of both EOCRC and LOCRC.

Conditions

• Early-onset Colorectal Cancer
• Late-onset Colorectal Cancer

Interventions

Type	Name	Description
OTHER	standardized treatment	Patients enrolled in these 2 cohorts all received standardized treatment of colorectal cancer.

Timeline

• Start date: 2008-01-01
• Primary completion: 2018-12-31
• Completion: 2023-06-30
• First posted: 2023-09-15
• Last updated: 2023-09-15