NCT06038071

Family Mid-Upper Arm Circumference (MUAC) Follow-up After Recovery From Acute Malnutrition (MODAM-fMUAC)

Efficacy and Safety of Family Mid-upper Arm Circumference (MUAC) After Recovery From Severe and Moderate Acute Malnutrition

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,600 (estimated)
• Sponsor: Action Against Hunger USA · Academic / Other
• Sex: All
• Age: 6 Months – 59 Months
• Healthy volunteers: Not accepted

Summary

Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. For the Family MUAC follow-up study, children who recover from these two parallel clinical trials will be enrolled in trial to test the effectiveness of MUAC screening at home by the child's caregivers as a self-referral strategy, compared to a scheduled health facility-led strategy and the standard of care of community-based follow-up visits.

Conditions

• Severe Acute Malnutrition
• Moderate Acute Malnutrition

Interventions

Type	Name	Description
OTHER	nutrition, IYCF, WASH education	nutrition, IYCF, WASH education
OTHER	scheduled anthropometric screening	anthropometric screening by health care workers at 1, 3, and 6 months
OTHER	family MUAC	family MUAC training for the primary caregiver present at the time of recovery

Timeline

• Start date: 2023-09-25
• Primary completion: 2026-09-25
• Completion: 2026-09-25
• First posted: 2023-09-14
• Last updated: 2024-07-16

Locations

3 sites across 1 country: Ethiopia