NCT06031883

Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia

Efficacy of Adding Low Dose Ketamine or Fentanyl to Propofol-dexmedetomidine as Total Intravenous Anesthesia for Patients Undergoing Craniotomy

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Minia University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Efficacy of adding low dose ketamine or fentanyl to propofol-dexmedetomidine as total intravenous anesthesia for patients undergoing craniotomy in supra tentorial brain tumor

Detailed description

Efficacy of adding low dose ketamine or fentanyl to propofol-dexmedetomidine as total intravenous anesthesia for patients undergoing craniotomy in supra tentorial brain tumor surgery on brain relaxation score, hemodynamics, surgeon satisfaction score , total requirement of intra operative propofol and post operative analgesia

Conditions

• Patients Undergoing Elective Craniotomy

Interventions

Type	Name	Description
DRUG	Ketamine	Total intravenous anesthesia in craniotomy

Timeline

• Start date: 2023-02-01
• Primary completion: 2024-12-01
• Completion: 2025-03-05
• First posted: 2023-09-11
• Last updated: 2025-07-30

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study