Clinical Trials Directory

Trials / Terminated

TerminatedNCT06029595

Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy

A 52-week, Randomised, Double Blind, Multicentre, 2-arm Parallel Group Trial Assessing Efficacy of CHF6001 (Total Daily Dose 3200μg) Dry Powder Inhaler (DPI) add-on to Maintenance Medium or High Dose of Inhaled Corticosteroids in Combination With Long-acting ß2-agonists in Subjects With Uncontrolled Asthma

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
517 (actual)
Sponsor
Chiesi Farmaceutici S.p.A. · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of CHF6001 (Tanimilast) as add-on to maintenance of inhaled corticosteroids in combination with Long-acting ß2-agonists in the target patient population. (TANGO)

Conditions

Interventions

TypeNameDescription
DRUGExperimental: CHF6001 3200 μg800 μg/actuation - 2 inhalations of CHF6001 800 μg twice daily (BID) total daily dose 3200 μg
DRUGPlacebo Comparator: CHF6001 Placebo2 inhalations of CHF6001 matching placebo BID

Timeline

Start date
2023-11-26
Primary completion
2025-12-09
Completion
2025-12-09
First posted
2023-09-08
Last updated
2025-12-18

Locations

187 sites across 14 countries: Argentina, Bulgaria, Czechia, Georgia, Germany, Hungary, Italy, Latvia, Lithuania, Poland, Romania, South Africa, South Korea, Spain

Source: ClinicalTrials.gov record NCT06029595. Inclusion in this directory is not an endorsement.