NCT06027424

Blood Pressure and Obstructive Sleep Apnea

The Changes in Blood Pressure in Patients With Obstructive Sleep Apnea Following an Overnight Sleep

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,037 (actual)
• Sponsor: Taipei Veterans General Hospital, Taiwan · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Bidirectional and causal relationship exists between obstructive sleep apnea (OSA) and hypertension in a dose-response manner, independent of confounding variables such as age, smoking, and body mass index. OSA is conventionally diagnosed and graded by apnea-hypopnea index (AHI). The relationship between AHI and changes of blood pressure deserves further investigation.

Detailed description

Approximately 50% of patients with obstructive sleep apnea (OSA) have hypertension; up to 30% of patients with hypertension have OSA, and the prevalence is even higher in those of resistant hypertension. OSA is conventionally diagnosed and graded by apnea-hypopnea index (AHI). This retrospective study aimed to determine if OSA severity and AHI have effect on blood pressure measurements and the nocturnal changes following an overnight sleep.

Conditions

• The Effects of Obstructive Sleep Apnea on Blood Pressure Measurement

Interventions

Type	Name	Description
OTHER	—	observational study, no intervention

Timeline

• Start date: 2022-10-26
• Primary completion: 2023-02-28
• Completion: 2023-07-16
• First posted: 2023-09-07
• Last updated: 2023-09-07

Locations

1 site across 1 country: Taiwan