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Trials / Recruiting

RecruitingNCT06026735

Non-small Cell Lung Cancer With Central Nervous System Metastasis

Comprehensive Profiling of Promising Biomarkers in Exosomes From Non-small Cell Lung Cancer With Central Nervous System Metastasis

Status
Recruiting
Phase
Study type
Observational
Enrollment
30 (estimated)
Sponsor
National Taiwan University Hospital · Academic / Other
Sex
All
Age
20 Years – 90 Years
Healthy volunteers
Not accepted

Summary

Cerebrospinal fluid was obtained from the cerebrospinal cavity of non-small cell lung cancer patients with central nervous system metastasis, blood was obtained from veins, and metastatic lung cancer tumor tissue was obtained from surgically resected brain tumors or meningeal tumors. Then comprehensively analyze the exosomes contained in the aforementioned samples, and compare and analyze the clinical data of the patients, so as to explore whether the cancer cell-related substances contained in the cerebrospinal fluid, blood and tumor tissue can be used to predict lung cancer metastasis and Bioindicators of treatment effect.

Conditions

Interventions

TypeNameDescription
OTHERlung cancer with brain /leptomeningeal metastasisCerebrospinal fluid was obtained from the cerebrospinal cavity of non-small cell lung cancer patients with central nervous system metastasis, blood was obtained from veins, and metastatic lung cancer tumor tissue was obtained from surgically resected brain tumors or meningeal tumors. Then comprehensively analyze the exosomes contained in the aforementioned samples, and compare and analyze the clinical data of the patients, so as to explore whether the cancer cell-related substances contained in the cerebrospinal fluid, blood and tumor tissue can be used to predict lung cancer metastasis and Bioindicators of treatment effect.

Timeline

Start date
2023-01-13
Primary completion
2027-12-01
Completion
2027-12-01
First posted
2023-09-07
Last updated
2023-09-07

Locations

1 site across 1 country: Taiwan

Source: ClinicalTrials.gov record NCT06026735. Inclusion in this directory is not an endorsement.

Non-small Cell Lung Cancer With Central Nervous System Metastasis (NCT06026735) · Clinical Trials Directory