NCT06021405

Koebner's Phenomenon in Psoriasis and Lichen Planus

A Prospective Study to Investigate the Pathophysiology of the Koebner's Phenomenon in Psoriasis and Lichen Planus

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Marie-Charlotte Brüggen · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Psoriasis and lichen planus often occur at mechanically irritated skin sites (e.g. tight clothing). The investigators would like to investigate this phenomenon in more detail in this study. For this purpose, the skin is specifically irritated at a small and cosmetically favorable site by tearing off scotch tape or rubbing with a wooden spatula. In order to be able to examine the inflammatory processes caused by the irritation more closely, a small skin sample and a skin swab are taken from the irritated area. This skin sample and the swab are repeated after three and fourteen days.

Conditions

• Kobner Phenomenon
• Psoriasis
• Lichen Planus

Interventions

Type	Name	Description
PROCEDURE	Tape stripping	a small area of skin will be tape-stripped with adhesive tape for up to 40 times and/or rubbed with a wooden spatula until the skin shows a slight erythema

Timeline

• Start date: 2025-09-01
• Primary completion: 2025-09-20
• Completion: 2025-09-20
• First posted: 2023-09-01
• Last updated: 2026-03-17