NCT06019611

Epidural Stimulation in Multiple Sclerosis

A Pilot Study to Explore the Use of Percutaneous Spinal Stimulation in Participants With Multiple Sclerosis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (actual)
• Sponsor: Kristin Zhao, PhD · Academic / Other
• Sex: All
• Age: 22 Years
• Healthy volunteers: Not accepted

Summary

A study to quantify changes in motor performance of epidural stimulation in progressive multiple sclerosis (MS) patients over the course of 12 rehabilitation sessions.

Detailed description

The purpose of this trial is to study spinal motor nerve response to electrical stimulation delivered directly to the epidural space, and to measure any changes in motor performance during 12 sessions over the course of one month.

Conditions

• Multiple Sclerosis
• Demyelinating Disorder
• Autoimmune Diseases

Interventions

Type	Name	Description
DEVICE	Percutaneous epidural stimulation	Abbott percutaneous trial lead for epidural neurostimulation (Model 3086) Abbott clinician programmer for epidural and dorsal root ganglion neurostimulation (Model 3874) Ripple Neuromed Nomad Neurostimulation System

Timeline

• Start date: 2023-09-11
• Primary completion: 2024-02-27
• Completion: 2024-02-27
• First posted: 2023-08-31
• Last updated: 2025-04-27
• Results posted: 2025-04-27

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study