NCT06019273

Impacts of Different ART Regimens on Lipid Metabolism in People Living With HIV

Impacts of Different ART Regimens on Lipid Metabolism in People Living With Human Immunodeficiency Virus

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 180 (estimated)
• Sponsor: First Affiliated Hospital of Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

To compare the dynamic changes of lipid metabolism of people living HIV who treated with different antiretroviral therapy (ART) regimens such as Biktarvy EVG/c/TAF/FTC, DTG/FTC/TDF, TDF/3TC/EFV, etc. And to assess the safety and efficacy of different antiretroviral therapy.

Detailed description

This was a prospective observational study aiming to evaluate dynamic changes of lipid metabolism in people living HIV who treated with different antiretroviral therapy (ART) regimens. At the same time, cardiovascular risk and the incidence of non-alcoholic fatty liver disease are assessed so as to compare the effects of different regimen on cardiovascular risk and NAFLD and hope to discover several cardiovascular risk-related individual lipid species.

Conditions

• HIV Infection
• Combined Antiretroviral Therapy

Timeline

• Start date: 2022-04-25
• Primary completion: 2024-04-25
• Completion: 2024-05-01
• First posted: 2023-08-31
• Last updated: 2023-09-01

Locations

1 site across 1 country: China