NCT06017622

Observational Study of THC Concentrations in Acute Cannabis-induced CNS Depression

Multi-center Observational Study of Plasma Concentrations of THC and Its Metabolites in Pediatric Patients Visiting Emergency Departments for Acute Cannabis-induced CNS Depression

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 36 (estimated)
• Sponsor: Anebulo Pharmaceuticals · Industry
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This observational study is being conducted to determine plasma concentrations of tetrahydrocannabinol (THC) and its metabolites, 11-OH-THC and THC-COOH, in plasma of pediatric patients who visit the emergency department due to acute cannabis-induced CNS depression.

Detailed description

This is a multi-center, prospective, cross-sectional observational study to determine the concentrations of tetrahydrocannabinol (THC) and its metabolites (and/or other cannabinoids) in the plasma of pediatric patients admitted to emergency departments with acute cannabis-induced CNS depression. .The study will explore the relationships between these concentrations and parameters such as demographics, symptom severity, time to symptom resolution, and clinical outcomes. Samples will be collected as part of standard clinical procedure without requiring study participants to spend additional time in the hospital.

Conditions

• Acute Cannabis-induced CNS Depression

Timeline

• Start date: 2023-06-01
• Primary completion: 2026-12-30
• Completion: 2026-12-30
• First posted: 2023-08-30
• Last updated: 2026-02-17

Locations

1 site across 1 country: United States