NCT06014619

Complications and Recurrences After Mohs Micrographic Surgery and Slow Mohs

Clinical Presentation and Surgical Outcomes in Patients With Skin Disorders Treated With Mohs Micrographic Surgery and Slow Mohs.

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 16 Years
• Healthy volunteers: Not accepted

Summary

Mohs micro-graphic surgery (Mohs) is a tissue-sparing, surgical treatment for different types of skin cancer (e.g. basal cell carcinoma, squamous cell carcinoma, lentigo maligna (melanoma). It is a procedure performed with frozen sections. Slow Mohs, a variant of micro-graphic surgery, is performed by formalin fixation and paraffin-embedded sections. Both in Mohs and Slow Mohs tumor margins are assessed to achieve complete removal. This study aims to investigate the clinical presentation and outcomes (i.e. complications and recurrence rates) in patients treated with Mohs or Slow Mohs in the dermatology department of the Maastricht University Medical Center+ in Maastricht, the Netherlands.

Conditions

• Skin Cancer
• Complication
• Complication of Surgical Procedure
• Complication,Postoperative
• Recurrence
• Recurrent Disease
• Cutaneous Squamous Cell Carcinoma
• Basal Cell Carcinoma
• Lentigo Maligna
• Lentigo Maligna Melanoma

Interventions

Type	Name	Description
PROCEDURE	Mohs surgery	Treatment of a skin disease by Mohs micrographic surgery technique (frozen sections).
PROCEDURE	Slow Mohs surgery	Treatment of a skin disease by Slow Mohs technique (formalin fixation and paraffin-embedded sections).

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-02-01
• Completion: 2025-06-01
• First posted: 2023-08-28
• Last updated: 2025-04-04

Locations

1 site across 1 country: Netherlands