Trials / Active Not Recruiting
Active Not RecruitingNCT06014580
Molecular and Epidemiological Characteristics of Endometrial Cancer in Brazil
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 276 (actual)
- Sponsor
- Latin American Cooperative Oncology Group · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
An evaluation of the molecular and epidemiological aspects of endometrial cancer in Brazil is necessary to understand the high frequency of advanced disease. A better understanding of the current situation will generate essential data for the future development of national or international cooperative programs that aim to improve outcomes in these patients and generate additional knowledge for much-needed clinical trials in this population.
Detailed description
This is a retrospective observational cohort study. In this study, we will include patients diagnosed with endometrium cancer from January 2016 to December 2019 in participating sites and collect data on demographics, clinicopathological characteristics, treatment patterns, and outcomes. Data will be collected from medical records in selected centers that comprise different regions of Brazil. The patient data sources will be the medical records of the patients. Patients will continue to receive treatment and clinical evaluations for endometrial cancer according to what is determined by their medical team, according to the usual standards of treatment and clinical practice of each center. To minimize patient selection bias, physicians should invite all consecutive eligible patients. This study also provides for the collection and archiving of tumor tissue material. The samples will be tested to characterize the molecular subtype of endometrial cancer and will be sequentially stored in a biorepository to enable future translational studies, according to national regulations.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observational study | This is an observational study; patients will not be exposed to clinical interventions different from those belonging to the standard of care. |
Timeline
- Start date
- 2023-11-27
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2023-08-28
- Last updated
- 2025-03-07
Locations
7 sites across 1 country: Brazil
Source: ClinicalTrials.gov record NCT06014580. Inclusion in this directory is not an endorsement.