NCT06013410

Pathophysiological Effects of Persistently Colonized Microbiome on Irritable Bowel Syndrome

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The goal of this clinical trial is to explore the pathophysiological effects of the persistently colonized microbiome in irritable bowel syndrome (IBS) patients. The main questions it aims to answer are: Question 1: the microbiome difference of the biofilm between IBS and healthy patients. Question 2: the metabolic product patterns between IBS and healthy patients. Participants will need to take a colonoscopy examination, two gut mucosal biopsy samples will be collected during the examination. Researchers will compare the IBS and healthy control groups to see if there was the disease-specific pattern in the microbiome and metabolic product of the biofilm.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	colonoscopy	colonoscopy

Timeline

• Start date: 2023-08-25
• Primary completion: 2026-05-10
• Completion: 2026-05-15
• First posted: 2023-08-28
• Last updated: 2023-08-28

Locations

1 site across 1 country: China