NCT06011018

Comparison of Effects of Mirror Therapy Combined With Neuromuscular Electrical Stimulation or Binaural Beats Stimulation on Cortical Excitability, Heart Rate Variability and Lower Limb Motor Function in Patients With Stroke

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (estimated)
• Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study aims to compare the effects of mirror therapy combined with either neuromuscular electrical stimulation or binaural beat stimulation on post-stroke lower limb motor function recovery. The study also explores the relationship between patients' cortical excitability and motor function improvement.

Conditions

• Stroke
• Healthy Adults

Interventions

Type	Name	Description
OTHER	Mirror Therapy	Sitting, mirror place at the midline between the legs. Unaffected leg is placed in front of the mirror and perform ankle dorsiflexion exercises. Duration: 5 seconds, Rest: 5 seconds
OTHER	Mirror Therapy + Electrical Stimulation	Same as the mirror therapy protocol. Affected leg: electrical stimulation on tibialis anterior muscle. Frequency: 35 Hz, Pulse width: 250µs, Duration: 5 seconds, Rest: 5 seconds.
OTHER	Mirror Therapy + Binaural Beat	Same as the mirror therapy protocol. Listen to music (pink noise), with 14Hz binaural beat stimulation

Timeline

• Start date: 2022-10-25
• Primary completion: 2026-07-31
• Completion: 2026-07-31
• First posted: 2023-08-25
• Last updated: 2025-09-04

Locations

1 site across 1 country: Taiwan