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UnknownNCT06010888

Fruquintinib With mFOLFOX6/FOLFIRI as First-Line Therapy for Conversion Surgery in mCRC

Fruquintinib With mFOLFOX6/FOLFIRI as First-Line Therapy for Conversion Surgery in mCRC: An Exploratory Clinical Trial

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
92 (estimated)
Sponsor
Fudan University · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The goal of this clinical trial is to learn about the efficacy and safety of Fruquintinib with mFOLFOX6/FOLFIRI in patients with mCRC. The main question it aims to answer is: The conversion surgery rate of the therapy mentioned above. The ORR, R0 surgery rate, DCR, PFS, OS, and safety will be evaluated.

Conditions

Interventions

TypeNameDescription
DRUGFruquintinib+mFOLFOX6/FOLFIRIFruquintinib: 4mg po qd, d1-d21, q4w with mFOLFOX6/FOLFIRI (standard)

Timeline

Start date
2023-10-31
Primary completion
2024-10-31
Completion
2026-03-31
First posted
2023-08-25
Last updated
2023-08-25

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT06010888. Inclusion in this directory is not an endorsement.

Fruquintinib With mFOLFOX6/FOLFIRI as First-Line Therapy for Conversion Surgery in mCRC (NCT06010888) · Clinical Trials Directory