NCT06010758

A Two-Week Study of an Anticavity Low pH Mouthwash

A Randomized Clinical Trial to Investigate Two-Week Clinical Safety, Changes in Salivary Flow and pH Following Use of an Anticavity Low pH Mouthwash

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 163 (actual)
• Sponsor: Johnson & Johnson Consumer Inc. (J&JCI) · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this clinical trial is to evaluate the oral tolerance of a new, experimental mouthwash compared to two mouth rinse formulations, which are already marketed, as well as compared to a tooth brushing only control group.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Listerine Experimental Mouthwash	After brushing for 1 timed minute, participants will rinse full strength for 1 minute with Listerine Experimental Mouthwash twice a day, morning and night.
DRUG	Colgate Cavity Protection Toothpaste	Participants will brush twice daily for 1 timed minute with Colgate Cavity Protection toothpaste.
DRUG	Listerine Total Care Zero	After brushing for 1 timed minute, participants will rinse full strength for 1 minute with Listerine Total Care Zero mouthwash twice a day, morning and night.
OTHER	Listerine Cool Mint Zero	After brushing for 1 timed minute, participants will rinse full strength for 30 seconds with Listerine Cool Mint Zero mouthwash twice a day, morning and night.

Timeline

• Start date: 2023-07-17
• Primary completion: 2023-08-03
• Completion: 2023-08-03
• First posted: 2023-08-25
• Last updated: 2024-01-12

Locations

1 site across 1 country: United States