NCT06010121

Comparison of Bioavailability of Liposomal and Traditional Formulation of Vitamin D3

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: AronPharma Sp. z o. o. · Industry
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study was to compare the profiles of 25-hydroxyvitamin D serum concentration in healthy adults after 4 weeks of using vitamin D supplementation either in a liposomal or a traditional formulation.

Detailed description

The study will be randomized, cross-over, participants will be randomly assigned to one of the study groups: A) the group receiving vitamin D3 in traditional formulation B) the group receiving vitamin D3 in liposomal formulation. The day before the start of supplementation (T0), 2 weeks (T1) and 4 weeks (T2) after the start of supplementation, participants will have their blood drawn. Then, after a wash-out period of 2 months, the groups will be switched. Participants will again receive daily supplementation with vitamin D3 for 4 weeks. Blood will be drawn before the start of supplementation (T0), 2 weeks (T1) and 4 weeks (T2) after the start of supplementation.

Conditions

• Bioavailability of Vitamin D

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Liposomal Vitamin D	2000 IU of cholecalciferol in liposomal formulation
DIETARY_SUPPLEMENT	Traditional Vitamin D	2000 IU of cholecalciferol in traditional formulation

Timeline

• Start date: 2023-02-17
• Primary completion: 2023-06-06
• Completion: 2023-06-06
• First posted: 2023-08-24
• Last updated: 2023-08-25

Locations

1 site across 1 country: Poland