Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06008938

An Observational Cohort Study to Characterize the Effectiveness and Safety of HEMGENIX® in Patients With Hemophilia B

An Observational Post-authorization Long-term Follow-up Study to Characterize the Effectiveness and Safety of HEMGENIX® (Etranacogene Dezaparvovec) in Patients With Hemophilia B

Status
Recruiting
Phase
Study type
Observational
Enrollment
500 (estimated)
Sponsor
CSL Behring · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This observational, post-authorization, long-term follow-up study aims to investigate the short and long-term effectiveness and safety of HEMGENIX in patients with hemophilia B. The study will also include a cohort of patients with hemophilia B treated with FIX prophylaxis to enable interpretation of relevant efficacy and safety findings of HEMGENIX.

Conditions

Interventions

TypeNameDescription
GENETICHEMGENIXHEMGENIX is a gene therapy medicinal product that aims to deliver a factor IX (FIX) gene expression cassette to the liver of patients with hemophilia B.
BIOLOGICALFactor IX (FIX)FIX prophylaxis therapy

Timeline

Start date
2023-06-15
Primary completion
2043-08-01
Completion
2043-08-01
First posted
2023-08-24
Last updated
2026-02-19

Locations

12 sites across 7 countries: United States, Austria, Denmark, France, Germany, Spain, Switzerland

Source: ClinicalTrials.gov record NCT06008938. Inclusion in this directory is not an endorsement.