Trials / Recruiting
RecruitingNCT06008392
INTERogating Cancer for Etiology, Prevention and Therapy Navigation
INTERogating Cancer for Etiology, Prevention and Therapy Navigation (INTERCEPTioN)
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 500 (estimated)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells and normal cells in the body. Researchers may request to access these data as they explore how to better prevent, screen, or treat cancer. This study is also being done to create a biobank (library) of samples and information to learn more about treating cancer. Discovery of genetic variants in patients with cancer could result in opportunities for cancer prevention, earlier diagnosis or better therapy for cancer.
Conditions
- Cancer
- Cancer Gene Mutation
- PAN Gene Mutation
- Hematopoietic and Lymphoid System Neoplasm
- Malignant Solid Neoplasm
Interventions
| Type | Name | Description |
|---|---|---|
| GENETIC | Pan-genomic Testing | Participants will be scheduled to review the study specifics, review consent and gather medical information. Once consented, samples will be collected. When the samples are received by Exact Sciences, DNA and RNA will be extracted, and sequencing will be performed. Following pan-genomic testing, participants will receive the full report with results from their care team and results will also be added to the patient's portal. If a germline finding is identified (positive pathogenic variant) the participant will also be referred for a genetic counselor visit. All results from the germline hereditary test will be reviewed by a certified genetic counselor in addition to a review of their pedigree. To help with review of any genetic research findings, the study team may request to obtain genomic data from previous genetic testing (clinical or research based). |
Timeline
- Start date
- 2023-10-12
- Primary completion
- 2033-09-01
- Completion
- 2033-09-01
- First posted
- 2023-08-23
- Last updated
- 2026-04-07
Locations
3 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT06008392. Inclusion in this directory is not an endorsement.