NCT06006663

Effect of Hebal and Synthetic Medicamentss on Enterococcus Feacalis

Antimicrobial Efficacy of Synthetic Versus Herbal Intracanal Medicaments Against Enterococcus Faecalis

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

this study aims to evaluate the antimicrobial efficacy of two synthetic (Ibuprofen, Modified triple antibiotic paste) and two herbal materials (Curcumin and Olive leaves extract) used as intracanal medication, against E.Faecalis in secondary endodontic infection cases.

Detailed description

we evaluate the antimicrobial efficacy of two synthetic (Ibuprofen, Modified triple antibiotic paste) and two herbal materials (Curcumin and Olive leaves extract) used as intracanal medication, against E.Faecalis in secondary endodontic infection cases by taking three samples from root canal , the first sample after removing gutta percha from root canal system, the second sample after shaping with protaper universal files and cleaning with 2.5% sodium hypochlorite , the third sample after 7 days from application of the medication . samples will be diluted into ten fold serial dilution and then the diluted samples will be cultured on bile esculin agar as it is selective media for enterococcus feacalis. bacterial reduction will be determined and comparision will be made .

Conditions

• Effective Intracanal Medicaments Against Enterococcus Faecalis

Interventions

Type	Name	Description
DRUG	Ibuprofen 400 mg.	synthetic intracanal medicament
DRUG	modified triple antibiotic paste	synthetic intracanal medicament
DIETARY_SUPPLEMENT	curcumin	herbal intracanal medicament
DIETARY_SUPPLEMENT	olive leaves extract	herbal intracanal medicament

Timeline

• Start date: 2023-08-26
• Primary completion: 2023-10-05
• Completion: 2023-12-10
• First posted: 2023-08-23
• Last updated: 2023-08-23