NCT06005714

Effect of Pharmacokinetics in Healthy Chinese Subjects

Effect of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Shanghai Vinnerna Biosciences Co., Ltd. · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study is a single-center, open label, self-controlled phase I clinical study, to evaluate the effects of clarithromycin or cyclosporine on pharmacokinetics of deuterium hydrobromide ramidvir tablets in healthy Chinese subjects.

Conditions

• The Effects of Clarithromycin or Cyclosporine on Pharmacokinetics of Deuterium Hydrobromide Ramidvir Tablets in Healthy Chinese Subjects

Interventions

Type	Name	Description
DRUG	Mindeudesivir hydrobromide tablets and Clarithromycin tablets	Mindeudesivir hydrobromide tablets are administered once at D1 and D4, and clarithromycin tablets are administered twice from D1 to D10.
DRUG	Mindeudesivir hydrobromide tablets and Cyclosporine softgels	Mindeudesivir hydrobromide tablets are administered once at D1 and D4, and cyclosporine sofgels are administered once at D4.

Timeline

• Start date: 2023-08-15
• Primary completion: 2023-10-31
• Completion: 2023-10-31
• First posted: 2023-08-22
• Last updated: 2025-06-29

Locations

1 site across 1 country: China