NCT06005207

Vaginal Progesterone Improves Clinical Outcomes of RIF Patients

A Single-center Randomized Controlled Trial of Vaginal Progesterone to Improve Clinical Pregnancy Outcomes in Patients With Repeated Implantation Failure

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 152 (estimated)
• Sponsor: Nanjing University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This study is a single-center, randomized, controlled prospective study. Those patients with repeated implantation failure (RIF) who will recieve frozen thawed embryo transfer (FET) are enrolled in the study. To determine the effect of vaginal progesterone on the clinical pregnancy outcomes of RIF patients.

Detailed description

According to the enrollment and exclusion criteria, the patients were enrolled, and the subjects were randomly divided into two groups by computer randomization. Group A was the vaginal progesterone added group (test group). Group B was the regular FET group (control group).

Conditions

• Infertility, Female

Interventions

Type	Name	Description
DRUG	progesterone vaginal sustained-release gel	90 mg progesterone vaginal sustained-release gel is added daily during endometrial transformation and luteal support

Timeline

• Start date: 2023-08-01
• Primary completion: 2024-12-31
• Completion: 2025-12-31
• First posted: 2023-08-22
• Last updated: 2023-08-22

Locations

1 site across 1 country: China