NCT06005129

Personality Change Study for Borderline Personality Disorder

Engaging Higher-Order Mechanisms of Psychopathology: A Parsimonious Approach to Precision Medicine

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Shannon E. Sauer-Zavala · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment. After the baseline period, participants will receive six weekly 50-60-minute treatment sessions. After the 6 treatment sessions, participants will complete a 4-week follow-up period to determine the sustainability of the treatment module.

Conditions

• Borderline Personality Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Personality-Based Therapy	Participants will be randomized to a 2- or 4-week assessment-only baseline period. After the baseline period, participants will receive the personality-based treatment module corresponding to their highest clinical elevation (i.e., neuroticism, \[low\] conscientiousness, \[low\] agreeableness). Treatment will consist of six weekly 50-60-minute sessions. After the 6-week intervention period, participants will complete a 4-week follow-up period to determine the sustainability of effects observed

Timeline

• Start date: 2024-09-15
• Primary completion: 2026-03-31
• Completion: 2026-03-31
• First posted: 2023-08-22
• Last updated: 2026-01-13

Locations

1 site across 1 country: United States