NCT06004063

Safety, Tolerability, and Efficacy of Enteral Nutrition Versus Standard of Care Nutrition in Hematopoietic Stem Cell Transplant Patients: A Pilot Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The goal of this research study is to learn if feeding someone after a stem cell transplant is safe and practical.

Detailed description

Primary Objective: a. To determine the feasibility, acceptability, and safety of NG tube feeding compared with patients not electing NG tube feeding. Secondary Objectives: 1. Determine the differential effects of enteral feeding versus Parenteral feeding on nutrition, and quality of life. 2. Determine the differential effects of enteral feeding versus parenteral feeding on survival and, medical comorbidities 3. Determine the differential effects of enteral feeding versus parenteral feeding on Fitbit data study for patients co-enrolled in Pediatric Energy Balance Data Repository Protocol PA18-0130. 4. Identify differential effects on microbiome for patients co-enrolled on MDACC protocol 2014-0938 "Longitudinal Biospecimen Acquisition for All Tumor Types And At-Risk Tissue 5. Determine adverse effects of enteral feeding in this population

Conditions

• Stem Cell

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Enteral nutrition (EN)	Given by Nasogastric Tube
OTHER	Standard care parenteral nutrition (PN)	Given by PO or Given by IV (vein)

Timeline

• Start date: 2023-08-04
• Primary completion: 2027-12-31
• Completion: 2029-12-31
• First posted: 2023-08-22
• Last updated: 2026-04-02

Locations

1 site across 1 country: United States