Clinical Trials Directory

Trials / Approved For Marketing

Approved For MarketingNCT06003881

Compassionate Use of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy

An Open-Label, Expanded Access Program of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)

Status
Approved For Marketing
Phase
Study type
Expanded Access
Enrollment
Sponsor
Regeneron Pharmaceuticals · Industry
Sex
All
Age
1 Year
Healthy volunteers

Summary

The program is to provide access to an experimental drug called pozelimab and to document the long-term safety of pozelimab in patients with Protein-Losing Enteropathy (PLE). CD55-deficient PLE/CHAPLE disease is a rare inherited disease of the immune system. This can be a life-threatening condition that is usually found when patients are children.

Conditions

Interventions

TypeNameDescription
DRUGPozelimabSubcutaneous (SC) administration

Timeline

First posted
2023-08-22
Last updated
2025-11-10

Source: ClinicalTrials.gov record NCT06003881. Inclusion in this directory is not an endorsement.