NCT05997693

One-Month DAPT in CABG Patients

One Month Dual Antiplatelet Therapy With Ticagrelor in Coronary Artery Bypass Graft Patients

• Status: Recruiting
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 700 (estimated)
• Sponsor: Weill Medical College of Cornell University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the effect of ticagrelor plus low-dose aspirin versus low-dose aspirin alone in patients with chronic coronary disease undergoing coronary artery bypass grafting.

Detailed description

A multinational, randomized trial to evaluate the effect of one-month of ticagrelor plus low-dose aspirin, versus low-dose aspirin alone, on the incidence of death, myocardial infarction, stroke, repeat revascularization and graft failure in patients with chronic coronary disease undergoing coronary artery bypass grafting.

Conditions

• Chronic Coronary Disease

Interventions

Type	Name	Description
DRUG	Ticagrelor 90 MG	Ticagrelor 90 mg twice daily taken orally for one month
DRUG	Low-dose aspirin	75-150 mg once daily taken orally

Timeline

• Start date: 2024-08-15
• Primary completion: 2027-01-01
• Completion: 2031-01-01
• First posted: 2023-08-18
• Last updated: 2025-12-22

Locations

22 sites across 6 countries: United States, Austria, Canada, China, Germany, Sweden

Regulatory

• FDA-regulated drug study