Trials / Unknown
UnknownNCT05996666
Primary Liver Cancer Early Detection
Early Detection of Primary Liver Cancer Based on cfDNA Methylation: A Multi-Center Case-Control Study (PRIMe-liver)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 701 (estimated)
- Sponsor
- The First Hospital of Jilin University · Academic / Other
- Sex
- All
- Age
- 18 Years – 74 Years
- Healthy volunteers
- Accepted
Summary
In the recently published multi-center, prospective, single-blind study (THUNDER study), using the methylation signal in cfDNA isolated from the peripheral blood to detect the six types of cancer, the sensitivity for liver cancer detection achieved 87.8%, with a specificity of 98.9%. In this study, a multicenter, case-control study is designed to establish an early cancer detection model based on cfDNA methylation biomarkers using qPCR to detect primary liver cancer and further validate the performance of the model.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Liver-cancer early detection test | Blood collection and liver-cancer early detection test |
Timeline
- Start date
- 2023-07-01
- Primary completion
- 2023-12-01
- Completion
- 2023-12-01
- First posted
- 2023-08-18
- Last updated
- 2023-08-18
Locations
2 sites across 1 country: China
Source: ClinicalTrials.gov record NCT05996666. Inclusion in this directory is not an endorsement.