NCT05994937

Cleaner Air for Lower Cardiometabolic Risk

Glycemic and Cardiometabolic Biomarker Improvements Associated With Reduction in Air Pollution Exposure

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this interventional sham-controlled pilot study is to study the effects of using portable air cleaners (PACs) in outpatient adults with prediabetes. The primary aims are to determine the effect PAC's have on glycemic variability and the concentrations of circulating biomarkers of inflammation.

Conditions

• PreDiabetes

Interventions

Type	Name	Description
DEVICE	PAC with HEPA filter intact	A commercially available PAC with a true HEPA filter will be used. Unit will be placed in the bedroom and used continuously (24 hours/day) for a total of 4 weeks.
DEVICE	PAC with HEPA filter removed	Uses the same model as the experimental PAC that is identical in appearance and sound with the HEPA filter removed . Unit will be placed in the bedroom and used continuously (24 hours/day) for a total of 4 weeks.

Timeline

• Start date: 2023-12-26
• Primary completion: 2026-02-28
• Completion: 2026-02-28
• First posted: 2023-08-16
• Last updated: 2025-12-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study