Trials / Completed
CompletedNCT05992961
The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 558 (actual)
- Sponsor
- Nordsjaellands Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury after non-cardiac surgery (MINS) and mortality. The majority of patients with MINS will not experience any symptoms, and thus MINS remains undetected without routine troponin measurements. The investigators hypothesized that implementing surveillance with troponin I as a standard care might be useful as risk stratification, and that increased surveillance, examinations, and subsequent individually based medical interventions, might improve the outcomes for patients with MINS.
Conditions
- Abdomen, Acute
- Myocardial Injury After Non-cardiac Surgery
- Troponin I
- Myocardial Injury
- Emergency Surgery
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Troponin I | Troponin I were measured 6-12 hours postoperatively and on each of the succeeding four postoperative days for patients operated March 1, 2019, to February 28, 2021. Patients with increased troponin I levels were assessed regarding symptoms of myocardial ischaemia including electrocardiography. Each patient was individually assessed, and relevant treatment and follow-up were planned in collaboration between surgeons, cardiologists, and anaesthesiologists. |
Timeline
- Start date
- 2018-02-01
- Primary completion
- 2021-02-28
- Completion
- 2021-02-28
- First posted
- 2023-08-15
- Last updated
- 2023-08-18
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT05992961. Inclusion in this directory is not an endorsement.