Trials / Unknown
UnknownNCT05991765
Evaluation of Digit Tip and Split Skin Donor Site Transcriptome
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 75 (actual)
- Sponsor
- University Hospital Schleswig-Holstein · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.
Detailed description
Regrowth of amputated fingertips presents a unique regenerative healing process in mammals, with subcutaneous volume regrowth, restoration of the dactylogram, and suppression of scar formation. In addition, wound healing from split-thickness donor sites shows almost scar-free healing. Transcriptome analysis is necessary to better understand the specific healing mechanisms of these two wound entities. Since no data are available to date, this study aims to fill the gap.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Digit Tip Wound | Digit Tip Wound Exudate Sample Collected while Dressing Change |
| OTHER | Split Skin Donor Site Wound | Split Skin Donor Site Wound Exudate Sample while Dressing Change |
Timeline
- Start date
- 2021-06-01
- Primary completion
- 2022-04-30
- Completion
- 2023-12-31
- First posted
- 2023-08-15
- Last updated
- 2023-08-15
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT05991765. Inclusion in this directory is not an endorsement.